Preheat the oven to 350℉ and line two muffin tins with cupcake liners.
In a medium bowl whisk together the flour, baking powder, baking soda, salt, cinnamon, nutmeg, cloves, and ginger. Set aside.
In a large bowl or using a stand mixer, cream together the softened butter and sugar until light and fluffy.
Beat in the applesauce, then add the buttermilk, vanilla extract, and eggs. Beat for 2 minutes until well combined.
Gradually add the dry flour mixture to the wet ingredients, mixing until just incorporated. Be careful not to overmix; stop as soon as there are no visible streaks of flour.
Divide the batter evenly among the cupcake liners, filling each about two-thirds full.
Bake in the center of the oven for 18-22 minutes or until a toothpick inserted into the center of a cupcake comes out clean.
Remove from the oven and let the cupcakes cool in the muffin tin for 5 minutes before transferring them to a wire rack to cool completely before frosting.